NFL picks, predictions for Week 6: Browns hand Cardinals first loss; Chargers, Payments, Packers keep scorching



The NFL season enters Week 6, and there are 5 matchups between groups with profitable information. 

The 1 p.m. ET options the renewal of the NFC North rivalry between the Packers and Bears, which can give rookie quarterback Justin Fields his first begin within the sequence. The red-hot Chargers additionally face the Ravens in a matchup between Justin Herbert and Lamar Jackson. 

The 4 p.m. ET slot additionally options two thrilling video games. AFC West surprises Las Vegas and Denver sq. off in a battle of groups making an attempt to maintain tempo within the division, and Heisman Trophy winners Kyler Murray and Baker Mayfield face off in a recreation between the Cardinals and Browns. 

Buffalo closes out the week with a visit to Tennessee on Monday Night time Soccer. That could be a slate filled with potential postseason matchups, and people video games will not be straightforward to select. 

Every week, Sporting Information will decide video games straight up. Here’s a have a look at our season totals: 

With that in thoughts, beneath are our picks and predictions for Week 6: 

Bills, Cowboys, Chargers serious contenders; Chiefs, 49ers drop for Week 6

NFL picks, predictions for Week 6: Browns hand Cardinals first loss; Chargers, Payments, Packers keep scorching
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NFL predictions for Week 6

  • Tampa Bay Buccaneers (-7) at Philadelphia Eagles 

Thursday, 8:20 p.m., FOX/NFL Community 

Bear in mind Tom Brady’s inexplicable loss on “Thursday Night time Soccer” towards the Bears final 12 months? Yeah, he most likely does too. The Eagles rank third within the league in cross protection (194.8) and shield the ball nicely, however Brady will press them with a high-flying offense. 

Choose: Buccaneers 31, Eagles 21 

Outcome: Buccaneers 28, Eagles 22

  • Miami Dolphins (-3) vs. Jacksonville Jaguars 

Sunday, 9:30 a.m., CBS

The Jaguars are going to listen to a couple of 20-game shedding streak all the best way to London. Each defenses enable greater than 30 factors per recreation, and the Jaguars have the worst turnover differential within the league. If Jacksonville quarterback Trevor Lawrence goes to win his first begin, then it’d as nicely be within the most-unlikely place. 

Choose: Jaguars 30, Dolphins 27 

  • Inexperienced Bay Packers (-6) at Chicago Bears 

Sunday, 1 p.m., FOX 

Fields will make his first begin towards the Packers. Aaron Rodgers is 21-5 towards the Bears, and that features 4 straight victories. If Fields desires to endear himself to the fanbase, then that is the sport to do it. The Bears have a top-10 statistical protection, however so do the Packers. Just a few turnovers offset a gradual begin for Inexperienced Bay on the highway. 

Choose: Packers 28, Bears 20 

NFL picks, predictions for Week 6: Browns hand Cardinals first loss; Chargers, Payments, Packers keep scorching
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  • Cincinnati Bengals (-3.5) at Detroit Lions 

Sunday, 1 p.m., FOX 

The Lions have misplaced two video games on last-second area targets. The Bengals are 2-2 in 4 video games determined by three factors. That standing of Joe Burrow (throat contusion) will have to be monitored all through the week, and Cincinnati wants to point out a better dedication to the operating recreation. Search for the Bengals to win one other tight one to separate their NFC North part of the schedule. 

Choose: Bengals 24, Lions 21 

  • Houston Texans at Indianapolis Colts (-10) 

Sunday, 1 p.m., CBS

The Colts are double-digit favorites at residence after 5 straight weeks as an underdog. Houston is 3-2 ATS as an underdog this season, and they’re catching the Colts on a brief week. This recreation can be nearer than anticipated.

Choose: Colts 29, Texans 22 

  • Los Angeles Rams (-8) at New York Giants 

Sunday, 1 p.m., FOX

The Rams are rolling with an offense that averages that second-most passing yards at 310.2 yards per recreation. Sean McVay may emphasize the operating recreation extra right here, too, particularly towards a Giants’ crew that’s checking out accidents with star offensive gamers Daniel Jones, Saquon Barkley and Kenny Golladay. 

Choose: Rams 35, Giants 18 

NFL picks, predictions for Week 6: Browns hand Cardinals first loss; Chargers, Payments, Packers keep scorching
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  • Kansas Metropolis Chiefs (-7) at Washington Soccer Group 

Sunday, 1 p.m., CBS

That is supposedly a get-right recreation for the Chiefs, however they cannot take that with no consideration on the highway at Washington. The excellent news is Washington has allowed 35.3 factors per recreation and generated simply two turnovers over the past three weeks. Kansas Metropolis stays affected person, and Patrick Mahomes will get them again to .500. 

Choose: Chiefs 34, Washington 24 

  • Minnesota Vikings (-2.5) at Carolina Panthers

Sunday, 1 p.m., FOX

Which quarterback do you belief extra? Sam Darnold has six TD passes and 6 interceptions. Kirk Cousins has 10 TDs and two interceptions. Working backs Dalvin Prepare dinner and Christian McCaffrey may return for this one, however it comes all the way down to which quarterback can keep away from that expensive mistake. 

Choose: Vikings 25, Panthers 22 

  • Los Angeles Chargers at Baltimore Ravens (-3) 

Sunday, 1 p.m., CBS

That is probably the most thrilling recreation within the early window, a battle between star quarterback Justin Herbert and Lamar Jackson. It is an early kick for a West Coast crew, and that is one thing to be cognizant of. However Los Angeles makes 3-0 on the highway in improbable vogue. 

Choose: Chargers 30, Ravens 27 

NFL picks, predictions for Week 6: Browns hand Cardinals first loss; Chargers, Payments, Packers keep scorching
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  • Arizona Cardinals at Cleveland Browns (-3.5) 

Sunday, 4:05 p.m., FOX 

The Cardinals and Browns each have elite offenses, and former Oklahoma Heisman winners Kyler Murray and Baker Mayfield will placed on a present. Which protection can get a cease in crunch time? Murray received the final head-to-head assembly in 2019, and the Cardinals have received the final 4 within the sequence. This one is in Cleveland, although, and the Browns knock the final unbeaten crew off. 

Choose: Browns 33, Cardinals 28 

  • Las Vegas Raiders at Denver Broncos (-4.5) 

Sunday, 4:25 p.m., CBS

The Raiders and Broncos are each caught in two-game slides after 3-0 begins, and this is a vital recreation to maintain tempo within the AFC West race. The Raiders swept this sequence final season, and Derek Carr will get the passing assault again on observe on the highway. 

Choose: Raiders 26, Broncos 24 

  • Dallas Cowboys (-3.5) at New England Patriots 

Sunday, 4:25 p.m., CBS 

The Cowboys are beginning to get somewhat hype with a balanced offense round Dak Prescott. Dallas has rushed for greater than 200 yards the final two weeks. The Pats rank fifth within the NFL in scoring protection and can attempt to gradual that momentum down, however New England will fall to 0-4 in residence video games this season. 

Choose: Cowboys 23, Patriots 20 

NFL picks, predictions for Week 6: Browns hand Cardinals first loss; Chargers, Payments, Packers keep scorching
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  • Seattle Seahawks at Pittsburgh Steelers (-4.5) 

Sunday, 8:20 p.m., NBC

Geno Smith takes over at starter for the Seahawks, and it is a robust task to face a Pittsburgh protection that has turned up the cross rush the final two weeks with the return of T.J. Watt. The Steelers get again to .500 with one other environment friendly efficiency from Ben Roethlisberger. 

Choose: Steelers 26, Seahawks 18 

  • Buffalo Payments (-5.5) at Tennessee Titans

Monday, 8:15 p.m., ESPN 

The Payments have a case as one of the best crew in soccer, however this can be a difficult matchup. Bear in mind Derrick Henry’s legendary stiff arm final 12 months? That was in a 42-16 victory towards Buffalo. Tennessee nonetheless is making an attempt to get Julio Jones again, and that would arrange an exhilarating AFC shootout. We’re not betting towards Josh Allen after making that mistake final week. 

Choose: Payments 35, Titans 31




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